MASTER'S DEGREE IN PHYSICAL AND ANALYTICAL CHEMISTRY - ANALYTICAL CHEMISTRY APPLIED TO THE STUDY AND DEVELOPMENT OF BIOMOLECULES (MACH)

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Diploma
BAC+5
Input level
BAC +3
Duration
2 years
Graduate
Yes
Locations
Jean-Henri Fabre Campus - AgES Institute
Study plan
Initial, Continuous
Internship
Mandatory
Cost of training

For more information, please contact us:

sec-mach-alternance@univ-avignon.fr

 

Sector
Agri-food - Physics, chemistry - Life sciences, biology
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Presentation

The aim of the "Analytical Chemistry Applied to the Study and Development of Biomolecules" (MACh) Master's degree is to train students with 5 years' higher education to have a solid foundation of theoretical and practical skills in chemistry applied to the analysis and characterisation of biomolecules. In particular, these skills focus on in-depth knowledge of the chemistry of natural substances and biopolymers (analysis and synthesis), as well as extraction, separation and spectroscopic techniques. These are complemented by the use of chemometrics, statistics and modelling tools. This Master's is also the only one in the region to teach the development of metabolomics approaches. In addition to these disciplinary fields, this Master's offers courses on knowledge of producing organisms (plants, animals and micro-organisms, etc.) and their metabolism in relation to their environment (chemical ecology).

Domain: Agrosciences, Environment and Health

Description : This text will be updated shortly.

Director : Stephane Nottin

Teaching and laboratory team

The teaching in this master's programme will be based on the nationally and internationally recognised skills of teacher-researchers in the chemistry department at Avignon Université in fields such as (non-exhaustive list):

  • the design and development of eco-extraction processes using natural matrices by the Green-SQPOV team,

  • chromatographic analysis of complex biological matrices by the EECAR-IMBE, GREEN and QuAlim-SQPOV teams, as well as the SAFE and S2CB ERITs at UPRI,

  • structural characterisation of organic molecules (metabolites and biopolymers) by the EECAR-IMBE, Green and QuAlim-SQPOV teams, and the 2 ERITs,

  • the development of metabolomic approaches by the EECAR-IMBE team and the 3A platform,

  • the design of eco-compatible formulations for and/or derived from green chemistry by the ERIT SAFE team or for food applications (micronutrients) by the QuAlim-SQPOV team,

  • the ecology, chemical ecology and heritage chemistry of the EECAR-IMBE team,

  • the modelling of extraction processes or complex environments by the UMR Green and QuAlim-SQPOV teams,

  • organic synthesis and transformation/functionalisation by hemisynthesis of natural molecules from the 2 ERITs and the QuAlim-SQPOV team.

Outline of the course

Admission

Admission requirements

Candidates must provide evidence of:

  • sound knowledge and skills associated with a degree in chemistry, physics-chemistry, physical sciences or biochemistry, including a good knowledge of techniques for analysing organic (bio)molecules,

  • a good command of the mathematical tools required for a Master's degree in chemistry,

  • good writing skills in French and a good level of English,

  • a good command of experimental procedures in the laboratory.



The relative academic level and relevance of the applications will be assessed by the teaching team on the basis of the following documents:

  • CV clearly showing the applicant's achievements and skills in relation to the course, as well as the coherence of their career plan and any professional experience they may have,

  • A letter of motivation written in French, setting out the applicant's reasons for taking the course and his or her knowledge of the training opportunities,

  • Transcripts of marks for the three years of the degree course (particular attention will be paid to marks or averages in subjects essential to the course and to the progression of averages),

  • For international students, transcripts of grades from three or four years of previous diplomas equivalent to the bachelor's degree,
    International students with foreign qualifications must also provide a certificate of proficiency in French at level B1 (CEFR).

For admission to Master 1 : apply online on the my master's platform

For admission to Master 2 : online admission or re-registration depending on your situation

Conditions for making a referral to the rector

Courses and levels

The course descriptions are published subject to approval by the Education and University Life Committee (CFVU) and may be subject to change.

M1 ANALYTICAL CHEMISTRY APPLIED TO THE STUDY AND DEVELOPMENT OF BIOMOLECULES (MACH)

Manager: Gerald Culioli Voir le courriel

Presentation of the course : During the first semester of the Master's programme, students will be introduced to fundamental concepts in analytical chemistry and, more specifically, will be trained in a wide range of extraction and separation techniques applicable to complex biological matrices. A Situational Analysis Activity (SAA) will provide a link between these different disciplines and enable them to be applied under real conditions to different types of biological matrix.
Essential concepts in organic synthesis, therapeutic chemistry and polymer chemistry will also be presented.
To complement these chemistry skills, biology modules on biomolecules (diversity, cellular compartmentalisation, etc.) and statistics (uni- and bivariate statistics, PCA, clustering, classification) will be offered to students.
Finally, throughout the semester, students will carry out a personalised scientific project as part of a research team (Avignon University, CNRS, INRAE). Dedicated courses (English, bibliography, IT tools, etc.) will enable students to acquire the additional skills they need to successfully complete their professional project.
Code
Courses and teaching units
Hourly volume
Coefficient
ECTS
S-U02-6001 UNIT 1-EXTRACTING AND ANALYSING THE CHEMICAL COMPOSITION OF A COMPLEX BIOLOGICAL MATRIX Hourly volume : 92.00 Coefficients : 10.00 Credits : 11.00
S-E02-5101 UCE 1 - FUNDAMENTALS OF ANALYTICAL CHEMISTRY & CHROMATOGRAPHIC TECHNIQUES Hourly volume : 32.50 Coefficients : 4.00 Credits : 5.00
S-E02-5102 UCE 2 - PROCESSING & EXTRACTION OF NATURAL MATRICES Hourly volume : 19.50 Coefficients : 2.00 Credits : 2.00
S-E02-5103 UCE 3 - AMS EXTRACTING AND ANALYSING A COMPLEX BIOLOGICAL MATRIX Hourly volume : 40.00 Coefficients : 4.00 Credits : 4.00
S-U02-6002 UNIT 2 - SYNTHESISING, ANALYSING AND ASSESSING THE THERAPEUTIC POTENTIAL OF BIO(MACRO)MOLECULES Hourly volume : 51.00 Coefficients : 8.00 Credits : 7.00
S-E02-5104 UCE 1 - ORGANIC CHEMISTRY Hourly volume : 27.00 Coefficients : 4.00 Credits : 4.00
S-E02-5105 UCE 2 - MOLECULAR (SUPRA/MACRO) CHEMISTRY 1 Hourly volume : 24.00 Coefficients : 4.00 Credits : 3.00
S-U02-6003 UNIT 3-DEVELOPING MULTIDISCIPLINARITY: BIOMOLECULES & CHEMOMETRICS Hourly volume : 36.00 Coefficients : 10.00 Credits : 6.00
S-E02-5106 UCE 1 - BIOMOLECULES Hourly volume : 12.00 Coefficients : 4.00 Credits : 2.00
S-E02-5107 UCE 2 - ANALYSIS OF MULTIVARIATE DATA IN CHEMOMETRICS Hourly volume : 24.00 Coefficients : 6.00 Credits : 4.00
S-U02-6006 UE 4-CONDUCTING A PROFESSIONAL INTEGRATION PROJECT & COMMUNICATING IN A SCIENTIFIC CONTEXT (INITIAL LEVEL) Hourly volume : 81.00 Coefficients : 7.00 Credits : 6.00
S-E02-5108 RESEARCH PROJECT (NON-WORK-LINKED STUDENTS ONLY) Hourly volume : 45.00 Coefficients : 5.00 Credits : 3.00
S-E02-5121 PREPARATION FOR PROFESSIONAL INTEGRATION Hourly volume : 12.00 Coefficients : Credits :
S-E02-5109 IN-COMPANY PERIOD (SANDWICH STUDENTS ONLY) Hourly volume : Coefficients : 5.00 Credits : 3.00
S-E02-5110 ENGLISH Hourly volume : 24.00 Coefficients : 2.00 Credits : 3.00

Presentation of the course : During the second semester of the Master's programme, students will continue to learn about analytical chemistry by studying in depth the spectroscopic techniques used to characterise the structure of biomolecules (IR, UV-Vis, 1D and 2D NMR, EPR and mass spectrometry).
At the same time, concepts of organic chemistry relating to the study of biomolecules (peptides, carbohydrates and nucleotides) and theoretical chemistry, enabling spectral data to be modelled, will be developed.
These chemistry lessons will be supplemented by multidisciplinary lessons in microbiology, chemical ecology and phytochemistry.
A Situation Analysis Activity (SAA) will then be dedicated to the purification and total structural characterisation of natural substances from complex biological matrices. Hemi-synthetic compounds will be developed and structure-activity relationships will be studied.
The research project initiated in the first semester will continue and may be extended as part of an internship at the end of the semester. Specific courses (English, ChemDraw training, Inkscape, etc.) will also be offered.
Code
Courses and teaching units
Hourly volume
Coefficient
ECTS
S-U02-6011 UNIT 1-CHARACTERISING THE CHEMICAL STRUCTURE OF BIOMOLECULES USING SPECTROSCOPIC TECHNIQUES Hourly volume : 69.00 Coefficients : 10.00 Credits : 8.00
S-E02-5111 UCE 1 - SPECTROSCOPIES Hourly volume : 36.00 Coefficients : 6.00 Credits : 5.00
S-E02-5112 UCE 2 - MASS SPECTROMETRY Hourly volume : 33.00 Coefficients : 4.00 Credits : 3.00
S-U02-6012 UNIT 2 - SYNTHESISING, STUDYING THE REACTIVITY AND MODELLING THE SPECTRAL PROPERTIES OF BIOMOLECULES Hourly volume : 53.00 Coefficients : 10.00 Credits : 7.00
S-E02-5113 UCE 1 - BIO-ORGANIC CHEMISTRY 1 Hourly volume : 33.00 Coefficients : 6.00 Credits : 4.00
S-E02-5114 UCE 2 - THEORETICAL CHEMISTRY 1 Hourly volume : 20.00 Coefficients : 4.00 Credits : 3.00
S-U02-6013 UNIT 3-DEVELOPING A MULTIDISCIPLINARY APPROACH: BASIC BIOLOGY & PHYTOCHEMISTRY Hourly volume : 37.00 Coefficients : 9.00 Credits : 5.00
S-E02-5115 UCE 1 - CHEMICAL ECOLOGY & MICROBIOLOGY Hourly volume : 22.00 Coefficients : 5.00 Credits : 3.00
S-E02-5116 UCE 2 - PHYTOCHEMISTRY Hourly volume : 15.00 Coefficients : 4.00 Credits : 2.00
S-U02-6014 EU 4-AMS Hourly volume : 40.00 Coefficients : 3.00 Credits : 4.00
S-E02-5117 AMS INTER-UE (UE 1 & UE 2) Hourly volume : 40.00 Coefficients : 3.00 Credits : 4.00
S-U02-6017 UE 5-CONDUCTING A PROFESSIONAL INTEGRATION PROJECT & COMMUNICATING IN A SCIENTIFIC CONTEXT (INTERMEDIATE LEVEL) Hourly volume : 68.50 Coefficients : 7.00 Credits : 6.00
S-E02-5118 PROFESSIONAL INTEGRATION: PREPARATION. OF THE PROJECT PROJECT. + IMMERSION PERIOD (WORK PLACEMENT IN ACADEMIC OR PRIVATE LABORATORY) Hourly volume : 45.50 Coefficients : 5.00 Credits : 3.00
S-E02-5122 PREPARATION FOR PROFESSIONAL INTEGRATION Hourly volume : 9.00 Coefficients : Credits :
S-E02-5119 IN-COMPANY PERIOD (SANDWICH STUDENTS ONLY) Hourly volume : 7.00 Coefficients : 5.00 Credits : 3.00
S-E02-5120 ENGLISH Hourly volume : 24.00 Coefficients : 2.00 Credits : 3.00

M2 ANALYTICAL CHEMISTRY APPLIED TO THE STUDY AND DEVELOPMENT OF BIOMOLECULES (MACH)

Manager: Raphael Plasson Voir le courriel

Presentation of the course : During the third semester of the Master's programme, students will develop advanced notions of analytical chemistry, with the aim of being able to set up a complete analytical workflow and implement the appropriate chemometrics tools to extract the relevant information. These approaches will be complemented by the use of numerical tools designed to predict and analyse the dynamic behaviour of physico-chemical systems. Additional concepts concerning the chemistry of lipids, emulsions and surfactants will also be developed.
The opening up to related sciences will be reinforced by the development of notions on metabolism and ecotoxicology. A series of lectures and seminars given by researchers from various backgrounds will be organised and followed by the students themselves throughout the semester.
A Situational Analysis Activity (SAA) will provide a link between these different disciplines and enable them to be applied in real-life conditions, via the development of a complete analytical workflow carried out on a targeted biological matrix.
Lastly, students will be able to acquire the skills needed to respond to calls for projects, skills that will be put to good use by putting together a research project in the form of a written document and an oral presentation.
Code
Courses and teaching units
Hourly volume
Coefficient
ECTS
S-U02-6021 UNIT 1 - DEVELOPING AN INTEGRATED ANALYTICAL WORKFLOW Hourly volume : 111.50 Coefficients : 10.00 Credits : 9.00
S-E02-5131 UCE 1 - OMICS & ADVANCED SEPARATIVE TECHNIQUES Hourly volume : 57.00 Coefficients : 5.00 Credits : 5.00
S-E02-5132 UCE 2 - CHEMOMETRICS Hourly volume : 54.50 Coefficients : 5.00 Credits : 4.00
S-U02-6022 UE 2-ANALYSING AND MODELLING THE EVOLUTION AND TRANSFORMATIONS OF EXPERIMENTAL CHEMICAL SYSTEMS Hourly volume : 87.00 Coefficients : 11.00 Credits : 8.00
S-E02-5133 UCE 1 - BIO-ORGANIC CHEMISTRY 2 Hourly volume : 21.00 Coefficients : 3.00 Credits : 2.00
S-E02-5134 UCE 2 - THEORETICAL CHEMISTRY 2 Hourly volume : 33.00 Coefficients : 4.00 Credits : 3.00
S-E02-5135 UCE 3 - MOLECULAR (SUPRA/MACRO) CHEMISTRY 2 Hourly volume : 33.00 Coefficients : 4.00 Credits : 3.00
S-U02-6023 UNIT 3-DEVELOPING MULTIDISCIPLINARITY: METABOLISM & ECOTOXICOLOGY Hourly volume : 56.00 Coefficients : 8.00 Credits : 3.00
S-E02-5136 UCE 1 - METABOLISM Hourly volume : 27.00 Coefficients : 5.00 Credits : 1.00
S-E02-5137 ECU 2 - ECOTOXICOLOGY Hourly volume : 9.00 Coefficients : 2.00 Credits : 1.00
S-E02-5138 UCE 3 - RESEARCH OPPORTUNITIES (CONFERENCES, SEMINARS, ETC.) Hourly volume : 20.00 Coefficients : 1.00 Credits : 1.00
S-U02-6024 EU 4-AMS Hourly volume : 40.00 Coefficients : 3.00 Credits : 4.00
S-E02-5139 AMS GLOBALE Hourly volume : 40.00 Coefficients : 3.00 Credits : 4.00
S-U02-6025 UE 5-CONDUCTING A PROFESSIONAL INTEGRATION PROJECT & COMMUNICATING IN A SCIENTIFIC CONTEXT (ADVANCED LEVEL) Hourly volume : 64.00 Coefficients : 7.00 Credits : 6.00
S-E02-5140 RESEARCH LABORATORY PROJECTS (NON-WORK-LINKED STUDENTS ONLY) Hourly volume : 40.00 Coefficients : 5.00 Credits : 3.00
S-E02-5141 IN-COMPANY PERIOD (SANDWICH STUDENTS ONLY) Hourly volume : Coefficients : 5.00 Credits : 3.00
S-E02-5142 ENGLISH Hourly volume : 24.00 Coefficients : 2.00 Credits : 3.00

Presentation of the course : For non-rotating students, the last semester will be entirely devoted to a placement in a research laboratory.
For sandwich students, this semester will consist of two long periods in companies, interspersed with a 15-day period dedicated to additional training (scientific communication, bibliographic monitoring, scientific software, data processing, etc.).
Code
Courses and teaching units
Hourly volume
Coefficient
ECTS
S-U02-6031 UE 1 - CARRYING OUT A PROFESSIONAL INTEGRATION PROJECT & COMMUNICATING IN A SCIENTIFIC CONTEXT (COMPETENT LEVEL) Hourly volume : 1.50 Coefficients : 10.00 Credits : 30.00
S-E02-5151 WORK PLACEMENT IN A RESEARCH LABORATORY (NON-ROTATING STUDENTS ONLY) Hourly volume : 1.50 Coefficients : 10.00 Credits : 30.00
S-U02-6034 UE 1 - CARRYING OUT A PROFESSIONAL INTEGRATION PROJECT & COMMUNICATING IN A SCIENTIFIC CONTEXT (COMPETENT LEVEL) Hourly volume : 97.00 Coefficients : 10.00 Credits : 30.00
S-E02-5152 IN-COMPANY PERIOD (SANDWICH STUDENTS ONLY) Hourly volume : 7.00 Coefficients : 8.00 Credits : 21.00
S-E02-5153 ADDITIONAL TRAINING (SANDWICH STUDENTS ONLY) Hourly volume : 75.00 Coefficients : 2.00 Credits : 9.00
S-E02-5154 PREPARATION FOR PROFESSIONAL INTEGRATION Hourly volume : 15.00 Coefficients : Credits :

Job opportunities

Sector: Specialised, scientific and technical activities.

Discipline : Analytical chemistry; Extraction techniques; Spectroscopies; Chromatography; Chemometrics; Analysis and development of biomolecules.

Job : Design engineer in chemistry/biotechnology; R&D project manager in chemistry/biotechnology; Design office manager; R&D analysis laboratory manager; R&D manager; Quality engineer (to be supplemented by quality training); Researcher in (bio)chemistry/biotechnology (after doctoral thesis); R&D design manager (to be supplemented by professional experience); Lecturer-researcher in (bio)chemistry (after doctoral thesis). Graduate careers : Degree in the process of being created (opening in September 2024 for the M1 and September 2025 for the M2).

Lifelong Learning

Relais Handicap

Training accessible to people with disabilities. Contact the Relais Handicap :
univ-avignon.fr/campus/accessibility/disability/

The SFTLV has a disability advisor:
accueil-fc@univ-avignon.fr
04 32 74 32 20

Applications
Contact

Training Manager
Tel: +33(0)4 90 16 29 92

sec-mach-alternance@univ-avignon.fr

Important documents and links

Once you have registered, you will be asked to use the Digital Working Environment (ENT). Find out how to use it: Digital Working Environment (ENT)

Continuing education rate

For more information, please contact us:

sec-mach-alternance@univ-avignon.fr

 

Validation of acquired experience (vae)

Tel. +33 (0)4 32 74 32 23
sec-vae@univ-avignon.fr

https://univ-avignon.fr/formations/formation-tout-au-long-de-la-vie/la-validation-des-acquis/

Practical information

Lifelong Learning

 

 

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Administrative registration and re-registration calendar
Download the syllabus

Contact

Practical information
Agrosciences, Environment and Health Institute

301, rue Baruch de Spinoza

BP 21239

84916 AVIGNON CEDEX 9

Tel.: 04.90.14.44.00

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